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We started with a formula that was effective for more than 75% of women. Then we made it better. 

When we set out to make PMS history, we wanted to find a natural way to help women tackle their biggest PMS problems. Our master herbalists wanted something safe and time-tested, so we started with one of the most widely prescribed traditional formulas for PMS. The base formula we chose is known for its anti-anxiety and antidepressant effects, as well as its ability to address the physical symptoms of PMS like fatigue, insomnia, breast pain, anxiety, irritability, mood swings, and tension.

What's Inside

  • The Fab Four: A proprietary blend of Chinese Peony Root, Bupleurum Root, Cyperus Rhizome, and Licorice Root are demonstrated to have anti-depressive effects, and are also know for their anti-inflammatory, antioxidant, and pain relieving effects.
  • Dong Quai Root: A powerfully anti-inflammatory herb that can decrease contraction in uterine muscles to relieve pain and cramping. Also has similar effects to serotonin to benefit mood.
  • Poria Sclerotium: A super-fungi known for it's ability to improve digestion and address symptoms like bloating, nausea, heartburn, and cravings.
  • Valerian Root: Known for its antispasmodic and relaxing effect on the uterus, it also helps relax tension and irritability.
  • Chinese Skullcap: An anti-inflammatory herb that also is know to decrease pain and anxiety. Additionally, Chinese Skullcap is hepatoprotective and supports detox and healthy liver function.
  • Curcuma: Contains highly anti-inflammatory compound curcumin that helps reduce chronic pain and spasm.
  • Atractylodes Rhizome: Included to reduce stress, anxiety, and to aid in healthy sleep and recovery. 
  • Our Proprietary Digestive Blend: A combination of licorice, honey, and mint helps with PMS symptoms like nausea, bloating, bowel changes, and cravings.
  • Our Proprietary Mental Health Blend: Silk Tree Bark and Polygala Root are traditionally used to improve mood  and soothe irritability, mental stress, and restlessness.

Made the right way, because it's the only way we know how. 

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Our all natural herbal tinctures are convenient, easy to take, and effective. A small 1oz bottle slips conveniently into your purse, so, unlike pills, it's easy to take on the go. Start taking Unwind at the first sign of PMS for maximum benefit. All of our formulas are proudly produced in the USA following current Good Manufacturing Practice (cGMP) standards.


Don't stress. We did the research, so you don't have to.

Peer-Reviewed Research Papers: 35+. Research Summary Read Time: 5-10 minutes.

When we set out to make PMS history, we wanted to find a natural way to help women tackle their biggest PMS problems. Our master herbalists wanted something safe and time-tested, so we started with one of the most widely prescribed traditional formulas for PMS. The base formula we chose is known for its anti-anxiety and antidepressant effects, as well as its ability to address the physical symptoms of PMS like fatigue, insomnia, breast pain, anxiety, irritability, mood swings, and tension.

We also wanted to make sure our formula was strong enough for even the worst PMS. In one study for PMDD, the most severe kind of PMS, the base formula we settled on was effective for more than 75% of women, with 46.7% of women achieving remission according to the HAM-D depression rating scale. 81% of patients at the conclusion of the study no longer met the DSM-IV criteria for PMDD. That sounded like a great place to start, so we set about making our formula the best in the biz. For more information, check out all the ingredient research below.

THE FAB FOUR

This powerful combination of peony root, bupleurum root, Chinese licorice root, and cyperus rhizome effectively improved the symptoms of PMS related depression, by helping to regulate Glu/GABA balance in the central nervous system, specifically by affecting neurotransmitters and receptors responsible for mood, memory, and other mental health conditions. While these herbs really shine when used together, each has unique functions in and of itself:

  • Chinese Peony and Tree Peony Roots: Herbs in the peony family are traditionally used for treating women’s health complaints. This powerful group of herbs have been shown to have analgesic (pain killing), anti-inflammatory, antioxidant, and immunomodulatory effects.

  • Bupleurum Root: Has inhibitory effects on the central nervous system (Kanba S, Yamada K, Mizushima H, Murata T, Asai M. Use of herbal medicine for treating psychiatric disorders in Japan. In : KanbaS, RichelsonE (eds). Herbal Medicine for Neuropsychiatric Diseases. Seiwa Shoten/Brunner-Mazel, New York, 1999; 3–13.)

  • Cyperus Rhizome: Several studies have identified the antioxidant and free radical scavenging activity of this plant. It has demonstrated high reduction capability and powerful free radical scavenging.

  • Licorice Root: When used in combination therapy, licorice root was effective at decreasing abnormal uterine bleedingin women with PCOS. More research is included in our digestive blend information below.

DONG QUAI ROOT

  • While dong quai root, also known as angelica root, has been used for centuries in traditional medicines for women’s health issues, researchers have identified the bioactive compound as Z-ligustilide — a powerful compound that inhibits contraction in uterine muscle and also improves microcirculation in uterine tissue. What does that mean in plain english? Ligustilide fights your worst cramping issues.

  • Ligustilide is also a powerful anti-inflammatory, which may help fight a number of period symptoms like pain and bloating.

  • Dong quai has also contains several chemical components that behave similarly to serotonin, a super important neurotransmitter that contributes to feelings of wellbeing and happiness. Serotonin is also involved in the regulation of sleep, mood, appetite (think cravings), memory, and learning. In fact, most pharmaceutical treatments for PMS include selective serotonin reuptake inhibitors (SSRIs) to improve serotonin levels.

FU LING PORIA SCLEROTIUM

  • Poria is traditionally used to benefit digestion. With its inclusion in similar formulas to Unwind, it’s been shown to be an effective treatment for functional dyspepsia, a condition with symptoms like stomach pain, bloating, nausea, loss of appetite, and heartburn (sounds a lot like PMS to us!). In a clinical trial of 180 women, those in the control group had a nearly 50% reduction in symptoms, improved motilin and gastrin levels, and better gastric emptying rates (think improved constipation)!

VALERIAN ROOT

CHINESE SKULLCAP ROOT

CURCUMA WENYUJIN ROOT

BAI ZHU ATRACTYLODES RHIZOME

OUR PROPRIETARY DIGESTIVE BLEND

OUR PROPRIETARY MENTAL HEALTH BLEND

  • Silk Tree Bark: Traditionally used for the treatment of depression, irritability, insomnia, and mood swings. We knew this would be the perfect way to complement our blend especially for the emotional rollercoaster of PMS.

  • Polygala Root: The traditional indications for polygala include insomnia, mental stress, pent up emotions, fuzzy headedness, and restlessness.